Abstract： AS 1807.22:2000 pdf download.Cleanrooms, workstations, safety cabinets and pharmaceutical isolators-Methods of test Method 22: Determination of air barrier containment of laminar flow safety cabinets. 7 PROCEDURE The procedure shall be as f...
AS 1807.22:2000 pdf download.Cleanrooms, workstations, safety cabinets and pharmaceutical isolators-Methods of test Method 22:
Determination of air barrier containment of laminar flow safety cabinets.
7 PROCEDURE The procedure shall be as follows:
(a) Set the cabinet in operation. Measure initial pressure drops across all HEPA filters and record the values.
(b) Set the aerosol photometer to the identical sensitivity level previously used to determine the filter and filter installation
integrity (see AS 1807.6).
NOTE: This should not be commenced until the background aerosol concentrations in the room have reached a steady stale.
(c) Set the air pressure on the aerosol generator at 140 ±5 kPa with a single Laskin noiile operating, release aerosol at a
distance of 25 ±1 mm from, and at right angles to the inside plane of the viewing window at a series of test positions with the
centre of the hose outlet 25 ±1 mm below the viewing window. The test positions shall be approximately 50 mm (centre ol hose) from both inner side walls of the cabinet and at intervals of approximately 100 mm between these points (see Figure I).
(d) Operate the aerosol photometer at each test position for at least 10 s. Where an intermittent penetration reading greater than 0.01% above the ambient concentration is obtained, continue for at least a further 30 s.
(e) Using the anemometer, measure the air velocity of the exhaust air on the face of the perforated, removable guard at its centre point and record the value.
(f) If adjustments are made to the exhaust filter air flow rate, laminar flow conditions for the cabinet should be re-checked in
accordance with AS 1807.1.
(g) Measure pressure drops across all FIEPA filters after barrier containment test and record the values.
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